Karl Swedberg Selected Research

Enalapril

1/2022	Angiotensin-neprilysin inhibition and renal outcomes across the spectrum of ejection fraction in heart failure.
1/2022	Effects of sacubitril/valsartan on glycemia in patients with diabetes and heart failure: the PARAGON-HF and PARADIGM-HF trials.
1/2022	Effect of sacubitril/valsartan on investigator-reported ventricular arrhythmias in PARADIGM-HF.
8/2021	Development and external validation of prognostic models to predict sudden and pump-failure death in patients with HFrEF from PARADIGM-HF and ATMOSPHERE.
1/2021	Clinical Characteristics and Outcomes of Patients With Heart Failure With Reduced Ejection Fraction and Chronic Obstructive Pulmonary Disease: Insights From PARADIGM-HF.
1/2021	Effect of sacubitril/valsartan vs. enalapril on changes in heart failure therapies over time: the PARADIGM-HF trial.
1/2019	Effects of Sacubitril/Valsartan on Biomarkers of Extracellular Matrix Regulation in Patients With HFrEF.
1/2019	Reduced loop diuretic use in patients taking sacubitril/valsartan compared with enalapril: the PARADIGM-HF trial.
12/2018	Growth differentiation factor-15 is not modified by sacubitril/valsartan and is an independent marker of risk in patients with heart failure and reduced ejection fraction: the PARADIGM-HF trial.
1/2018	Effect of sacubitril/valsartan on recurrent events in the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF).

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Karl Swedberg Research Topics

Disease

278	Heart Failure 04/2022 - 01/2000
42	Systolic Heart Failure 04/2022 - 07/2003
22	Myocardial Infarction 01/2020 - 08/2002
20	Left Ventricular Dysfunction 01/2020 - 08/2002
14	Hypotension (Low Blood Pressure) 01/2018 - 09/2003
13	Diabetes Mellitus 01/2020 - 07/2005
13	Atrial Fibrillation 01/2020 - 07/2005
11	Cardiomyopathies (Cardiomyopathy) 01/2021 - 07/2002
10	Sudden Death 01/2022 - 10/2004
10	Stroke (Strokes) 11/2017 - 02/2005
10	Hyperkalemia 01/2017 - 10/2004
8	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 03/2009
8	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 03/2002
7	Dyspnea (Shortness of Breath) 01/2016 - 03/2007
6	Anemia 04/2022 - 02/2006
5	Edema (Dropsy) 01/2019 - 03/2007
5	Hypertension (High Blood Pressure) 12/2015 - 01/2006
5	Body Weight (Weight, Body) 07/2012 - 05/2005
4	Chronic Renal Insufficiency 01/2018 - 12/2012
4	Disease Progression 01/2017 - 06/2013
4	Acute Coronary Syndrome 09/2015 - 12/2003
4	Bradycardia 05/2015 - 09/2010
4	Unstable Angina 03/2007 - 08/2002
3	Respiratory Sounds (Crackle) 01/2022 - 12/2005
3	Shock 01/2022 - 02/2005
3	Bundle-Branch Block (Fascicular Block) 08/2021 - 09/2013
3	Cardiac Sudden Death (Sudden Cardiac Arrest) 10/2020 - 08/2015
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2019 - 08/2013
3	Hyponatremia 10/2015 - 03/2007
3	Cough 09/2014 - 09/2003
2	Cardiac Arrhythmias (Arrythmia) 01/2022 - 07/2002
2	Coronary Disease (Coronary Heart Disease) 10/2017 - 10/2015
2	Human Influenza (Influenza) 02/2016 - 03/2007
2	Hypokalemia 03/2015 - 05/2005

Drug/Important Bio-Agent (IBA)

57	candesartanIBA 08/2021 - 01/2000
50	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2021 - 01/2000
43	sacubitril and valsartan sodium hydrate drug combinationIBA 01/2022 - 07/2014
33	IvabradineIBA 12/2019 - 01/2010
29	Enalapril FDA LinkGeneric 01/2022 - 08/2002
27	Neprilysin (Neutral Endopeptidase)IBA 01/2022 - 08/2002
27	Tolvaptan FDA Link 01/2018 - 05/2005
26	Vasopressins (Vasopressin)IBA 01/2018 - 05/2005
23	Mineralocorticoid Receptor AntagonistsIBA 01/2022 - 09/2004
23	Angiotensin Receptors (Angiotensin II Receptor)IBA 01/2021 - 08/2003
20	Eplerenone (Inspra)FDA LinkGeneric 01/2021 - 06/2005
20	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2021 - 09/2004
20	Angiotensin Receptor AntagonistsIBA 01/2021 - 03/2004
17	Pharmaceutical PreparationsIBA 01/2019 - 10/2004
16	Carvedilol (Coreg)FDA LinkGeneric 01/2015 - 06/2002
16	Metoprolol (Toprol-XL)FDA LinkGeneric 01/2015 - 06/2002
14	DiureticsIBA 01/2022 - 07/2003
14	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2017 - 01/2000
13	CreatinineIBA 08/2021 - 10/2004
13	pro-brain natriuretic peptide (1-76)IBA 01/2021 - 04/2006
12	Natriuretic PeptidesIBA 01/2021 - 08/2010
10	Valsartan (Vals)FDA Link 01/2022 - 08/2003
8	Darbepoetin alfa (Aranesp)FDA Link 04/2022 - 08/2009
8	Hemoglobins (Hemoglobin)IBA 01/2018 - 02/2006
7	AngiotensinsIBA 01/2022 - 07/2005
7	aliskiren FDA Link 08/2021 - 08/2010
6	PotassiumIBA 01/2020 - 11/2007
5	Irbesartan FDA LinkGeneric 08/2021 - 01/2015
5	Biomarkers (Surrogate Marker)IBA 12/2019 - 06/2002
5	SodiumIBA 01/2019 - 03/2007
4	Insulin (Novolin)FDA Link 01/2022 - 03/2017
4	AnticoagulantsIBA 11/2017 - 07/2010
4	AldosteroneIBA 01/2017 - 05/2012
4	Spironolactone (Aldactone)FDA LinkGeneric 02/2008 - 06/2005
3	paragonIBA 01/2022 - 01/2021
3	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 08/2021 - 01/2014
3	Glucose (Dextrose)FDA LinkGeneric 12/2017 - 07/2005
3	flosequinanIBA 01/2017 - 11/2002
3	SaltsIBA 11/2013 - 03/2007
3	Digoxin (Digitek)FDA LinkGeneric 12/2012 - 01/2006
3	Captopril (Capoten)FDA LinkGeneric 02/2006 - 08/2003
2	Growth Differentiation Factor 15IBA 04/2022 - 12/2018
2	ReninIBA 01/2021 - 07/2005
2	Therapeutic UsesIBA 01/2020 - 01/2018
2	Peptides (Polypeptides)IBA 01/2020 - 01/2017
2	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2019 - 03/2004
2	Uric Acid (Urate)IBA 01/2018 - 12/2014
2	Indicators and Reagents (Reagents)IBA 10/2017 - 10/2006
2	Endothelin Receptors (Endothelin Receptor)IBA 01/2017 - 02/2005
2	Bosentan (Tracleer)FDA Link 01/2017 - 02/2005
2	Vasodilator Agents (Vasodilators)IBA 01/2017 - 11/2002
2	Endothelins (Endothelin)IBA 01/2017 - 02/2005
2	Endothelin Receptor AntagonistsIBA 01/2017 - 02/2005
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2016 - 07/2010
2	CholesterolIBA 04/2015 - 03/2007
2	Antidiuretic Hormone Receptor AntagonistsIBA 05/2014 - 03/2007
2	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 06/2013 - 03/2007

Therapy/Procedure

80	Therapeutics 01/2022 - 04/2002
7	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 01/2022 - 12/2008
5	Patient Readmission 01/2016 - 01/2007
4	Defibrillators (Defibrillator) 01/2022 - 12/2012
3	Drug Tapering 01/2019 - 11/2007
3	Length of Stay 10/2015 - 05/2012
3	Critical Care (Surgical Intensive Care) 01/2015 - 10/2008
2	Cardiac Resynchronization Therapy 01/2022 - 12/2009
2	Drug Therapy (Chemotherapy) 01/2018 - 07/2013